drug abuse

Amphetamine Abuse

Amphetamine abuse is a common problem in today’s society, with many individuals using the drug for its stimulating effects. Amphetamines are a class of drugs that are prescribed to treat conditions like ADHD, narcolepsy, and obesity. However, when used inappropriately or without a prescription, they can cause serious harm to the body and mind.

Case: A 25-year-old man presents to the emergency room with symptoms of amphetamine overdose. He has a history of recreational amphetamine abuse and admits to taking a large quantity of the drug. He is agitated, restless, and has an elevated heart rate and blood pressure.


Amphetamines work by increasing the levels of neurotransmitters like dopamine and norepinephrine in the brain. These neurotransmitters are responsible for regulating mood, attention, and arousal. When amphetamines are used in excess, they can cause these neurotransmitter levels to become abnormally high, leading to overstimulation of the central nervous system. This can result in a range of symptoms, including agitation, anxiety, hyperactivity, and elevated heart rate and blood pressure.

Signs and Symptoms

The signs and symptoms of amphetamine abuse can vary depending on the individual and the dosage of the drug. Common symptoms include:

  • Agitation and restlessness
  • Anxiety and panic attacks
  • Hyperactivity and impulsivity
  • Elevated heart rate and blood pressure
  • Insomnia
  • Loss of appetite and weight loss
  • Dilated pupils
  • Sweating and tremors

Long-term complications

Long-term use of amphetamines can lead to a range of health problems, including:

  • Cardiovascular issues such as high blood pressure, heart disease, and stroke
  • Respiratory problems such as chronic bronchitis and asthma
  • Neurological issues such as seizures, headaches, and Parkinson’s-like symptoms
  • Gastrointestinal problems such as constipation and stomach pain
  • Mental health issues such as anxiety, depression, and psychosis
  • In addition to the physical and mental health risks, amphetamine abuse can also have social and legal consequences, such as job loss, financial problems, and criminal charges.


The diagnosis of amphetamine abuse is typically made based on a thorough physical exam and a review of the individual’s medical history and drug use. Blood and urine tests may be used to confirm the presence of amphetamines in the system and to check for any other underlying health issues that may be contributing to the symptoms.


The treatment of amphetamine abuse typically involves a combination of behavioral therapy and medications. In severe cases of amphetamine overdose, hospitalization may be required. Behavioral therapy can help individuals overcome their addiction and develop healthier coping mechanisms. Medications like antidepressants and antipsychotics may also be prescribed to help manage symptoms like anxiety and depression.

Dos and Don’ts


  • Seek medical attention if you or someone you know is experiencing symptoms of amphetamine abuse or overdose.
  • Participate in behavioral therapy or support groups to help overcome addiction.
  • Take medications as prescribed by a healthcare professional.


  • Do not use amphetamines without a prescription or medical supervision.
  • Do not mix amphetamines with other drugs or alcohol.
  • Do not ignore the signs and symptoms of amphetamine abuse or overdose.


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