Anti-phospholipid antibodies (aPL)

Anti-phospholipid antibodies (aPL) are a group of autoantibodies that target phospholipid-binding proteins and negatively charged phospholipids. These antibodies are associated with an increased risk of thrombosis and recurrent pregnancy loss. The anti-phospholipid antibody test is used to diagnose the presence of aPL in the blood. In this article, we will discuss the anti-phospholipid antibody test, including its uses, procedure, and normal values.

Uses of Anti-Phospholipid Antibody Test

The anti-phospholipid antibody test is used to diagnose the presence of aPL in the blood. This test is typically ordered when a person has symptoms that suggest a blood clot or when a woman has had recurrent pregnancy losses. The test may also be ordered as part of a routine health check-up for people who are at a higher risk of developing blood clots.

Procedure

The anti-phospholipid antibody test is a simple blood test that can be done in a doctor’s office or lab. The procedure involves taking a blood sample from the patient, which is then sent to a laboratory for analysis. The results of the test are typically available within a few days.

Normal Values

The normal values for the anti-phospholipid antibody test are as follows:

Antibody Normal Range
IgG Anti-Cardiolipin <15 MPL or <20 GPL
IgM Anti-Cardiolipin <12 MPL or <15 GPL
Beta-2 Glycoprotein 1 <20 U/mL

Frequently Asked Questions

What are anti-phospholipid antibodies?

Anti-phospholipid antibodies (aPL) are a group of autoantibodies that target phospholipid-binding proteins and negatively charged phospholipids.

What is the anti-phospholipid antibody test?

The anti-phospholipid antibody test is used to diagnose the presence of aPL in the blood.

Why is the anti-phospholipid antibody test done?

The test is typically ordered when a person has symptoms that suggest a blood clot or when a woman has had recurrent pregnancy losses.

How is the anti-phospholipid antibody test done?

The anti-phospholipid antibody test is a simple blood test that can be done in a doctor’s office or lab.

Reference

National Institutes of Health. (2021). Antiphospholipid Antibody Syndrome. https://www.nhlbi.nih.gov/health-topics/antiphospholipid-antibody-syndrome

Lab Tests Online. (2021)

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