Coagulation Profile: Understanding Blood Clotting

Blood clotting is a vital process that prevents excessive blood loss after an injury. However, when blood clots form inside the blood vessels without an injury, it can lead to serious health problems such as stroke, heart attack, and deep vein thrombosis. The coagulation profile is a blood test that measures how well the blood clots. This article will explain the coagulation profile, its normal values, and frequently asked questions.

What is the coagulation profile?

The coagulation profile is a blood test that measures the clotting factors in the blood. Clotting factors are proteins produced by the liver that help the blood to clot. The coagulation profile measures the levels of these clotting factors and evaluates how well the blood clots.

Why is the coagulation profile important?

The coagulation profile is important for diagnosing and monitoring blood clotting disorders such as hemophilia, von Willebrand disease, and deep vein thrombosis. It is also used to monitor the effectiveness of blood-thinning medications such as warfarin and heparin.

What are the normal values of the coagulation profile?

The following table shows the normal values of the coagulation profile:

Coagulation Test Normal Value
Prothrombin Time (PT) 11-13.5 seconds
International Normalized Ratio (INR) 0.8-1.1
Activated Partial Thromboplastin Time (aPTT) 25-35 seconds
Fibrinogen 200-400 mg/dL
D-Dimer < 500 ng/mL

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