HLA-B27 Test

The HLA-B27 test is a medical examination that determines whether an individual has the HLA-B27 gene. The HLA-B27 gene is a type of human leukocyte antigen (HLA) gene that plays a crucial role in the immune system. This article will explain what the HLA-B27 test is, why it is performed, what the results mean, and other essential information about the test.

What is the HLA-B27 test?

The HLA-B27 test is a blood test that determines whether an individual has the HLA-B27 gene. The test is usually ordered by a doctor if they suspect the patient has an autoimmune disease, especially if the patient has symptoms of inflammatory arthritis. The test detects the presence of the HLA-B27 antigen, which is a protein produced by the HLA-B27 gene.

Why is the HLA-B27 test performed?

The HLA-B27 test is performed to help diagnose autoimmune diseases, especially those that affect the joints. The HLA-B27 gene is strongly associated with several autoimmune diseases, including ankylosing spondylitis, reactive arthritis, and psoriatic arthritis. Individuals with the HLA-B27 gene are at a higher risk of developing these diseases than those without the gene.

What do the results of the HLA-B27 test mean?

If the HLA-B27 test is positive, it means that the individual has the HLA-B27 gene. However, having the gene does not mean that the individual will develop an autoimmune disease. Many people with the HLA-B27 gene do not have any symptoms of autoimmune diseases. On the other hand, if the test is negative, it means that the individual does not have the HLA-B27 gene. However, a negative test does not rule out the possibility of having an autoimmune disease.

Normal values

The normal value for the HLA-B27 test is negative, indicating that the individual does not have the HLA-B27 gene. However, it is important to note that a negative test does not rule out the possibility of having an autoimmune disease.

How long does it take to get the HLA-B27 test results?

The HLA-B27 test results are usually available within a few days.

Is the HLA-B27 test painful?

No, the HLA-B27 test is a simple blood test and is not painful.

Is the HLA-B27 test expensive?

The cost of the HLA-B27 test varies depending on the location and the healthcare provider. It is recommended to consult with the healthcare provider about the cost of the test.

Can the HLA-B27 test diagnose autoimmune diseases?

The HLA-B27 test alone cannot diagnose autoimmune diseases, but it can be a helpful tool in conjunction with other medical examinations.