Lupus Anticoagulant Test

Lupus anticoagulant (LA) is an autoimmune disorder that causes an increase in blood clotting, leading to a high risk of thrombosis or other blood clot-related complications. The lupus anticoagulant test is a laboratory test used to diagnose LA in patients. In this article, we will explain what the lupus anticoagulant test is, how it works, and answer some frequently asked questions about it.

What is the Lupus Anticoagulant Test?

The lupus anticoagulant test is a blood test that measures the presence of specific antibodies in the blood that are associated with LA. These antibodies, known as lupus anticoagulant antibodies, interfere with the body’s normal blood clotting process, leading to an increased risk of blood clots.

How does the Lupus Anticoagulant Test work?

The lupus anticoagulant test is a type of coagulation test that measures the clotting time of blood. The test involves mixing a patient’s blood with a substance that triggers clotting, such as calcium and a clotting factor called phospholipid. If the patient has lupus anticoagulant antibodies, the clotting time will be prolonged, indicating a high risk of blood clots.

What are the normal values for the Lupus Anticoagulant Test?

The lupus anticoagulant test results are reported in terms of the ratio of the patient’s clotting time to a control clotting time. A ratio greater than 1.2 is considered abnormal and indicates the presence of lupus anticoagulant antibodies. Normal values for the lupus anticoagulant test are summarized in the following table:

Ratio Interpretation
<1.2 Normal
1.2-1.3 Borderline
>1.3 Abnormal

FAQs about Lupus Anticoagulant Test

Why is the Lupus Anticoagulant Test performed?

The lupus anticoagulant test is performed to diagnose lupus anticoagulant, which is associated with an increased risk of blood clots. It is typically ordered when a patient has a history of blood clots or when a patient is suspected to have an autoimmune disorder.

What factors can affect the accuracy of the Lupus Anticoagulant Test?

Certain medications, such as heparin, can interfere with the lupus anticoagulant test and lead to a false positive result. Additionally, other factors, such as pregnancy, liver disease, and certain infections, can affect the accuracy of the test.

What is the treatment for lupus anticoagulant?

Treatment for lupus anticoagulant typically involves the use of blood thinners, such as warfarin or heparin, to reduce the risk of blood clots.

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